Definition of Pseudotumor cerebri: Pseudotumor cerebri: Increased pressure within the brain in the absence of a tumor. Symptoms may include headache, nausea, vomiting, pulsating intracranial noises, singing in the ears, double vision, loss of visual accuracy, and even blindness. It is most common in women between the ages of 20 and 50. The cause is usually not known. The condition is associated sometimes with the use of tetracycline, nalidixic acid, nitrofurantoin, phenytoin, lithium, and amiodarone, and the overuse of vitamin A. Diagnosis is by brain imaging and lumbar puncture. Drugs to reduce cerebrospinal fluid production or hyperosmotic drugs may be used to reduce fluid buildup. Excess cerebrospinal fluid may be removed by repeated spinal taps, shunting or a type of surgery called optic nerve sheath fenestration that allows the excess fluid to escape. Steroids may be prescribed to reduce swelling of brain tissue. Pseudotumor cerebri is also called benign intracranial hypertension.
Urticaria, nephritis, and pseudotumor cerebri. Department of Rheumatic and Immunologic Disease, Cleveland Clinic Foundation, Ohio 44195.
The spectrum of chronic urticarial disease ranges from chronic urticarial skin lesions alone to well-characterized systemic lupus erythematosus with urticarial vasculitis as the major skin manifestation. Within this spectrum is the syndrome of urticarial vasculitis associated with systemic disease manifestations. There have been six previously recorded cases of urticarial vasculitis associated with pseudotumor cerebri. At least two of these have included membranoproliferative glomerulonephritis. The authors report a case of chronic urticarial disease associated with pseudotumor cerebri and membranoproliferative glomerulonephritis, but without demonstrable vasculitis. It is possible that this represents a distinct entity within the spectrum of chronic urticarial disease and cca be easily screened for in clinical practice. PubMed Article on Urticaria, nephritis,and pseudotumor cerebri.
Definition of Vasculitis: A varied group of disorders which all share a common underlying problem of inflammation of a blood vessel or blood vessels. The inflammation may affect any size blood vessel, anywhere in the body. It may affect either arteries and/or veins. The inflammation may be focal, meaning that it affects a single location within a vessel; or it may be widespread, with areas of inflammation scattered throughout a particular organ or tissue, or even affecting more than one organ system in the body.
Authors Jerry D Brewer, MD Mark DP Davis, MD Section Editors John H Stone, MD, MPH Sarbjit Saini, MD Deputy Editor Anna M Feldweg, MD
Last literature review version 16.3: October 2008 | This topic last updated: September 19, 2007 (More)
INTRODUCTION — Urticarial vasculitis (UV) is considered a clinicopathologic entity consisting of two elements:
Clinical manifestations of urticaria Histopathological evidence of cutaneous leukocytoclastic vasculitis (LCV) of the small vessels, largely involving the postcapillary venules [1-4]. Although UV is most commonly idiopathic, it can occur in association with autoimmune diseases, drug reactions, infections, or malignancy. UV may be systemic or localized to the skin [5]. Hypocomplementemia, when present, may be associated with extensive vasculitis and systemic features that most commonly involve the musculoskeletal, pulmonary, renal, and/or gastrointestinal systems. Discussion of this topic is confounded by the lack of accepted criteria for distinguishing UV from other cutaneous vasculitides and associated conditions.
A detailed review of the literature has been published by the authors [6]. A practical approach is presented here. The epidemiology, clinical features, laboratory and biopsy findings, differential diagnosis, and prognosis of UV will be reviewed herein. (See "Etiology and diagnosis of urticaria" for a more general discussion of urticaria and related conditions).
TERMINOLOGY — UV is characterized by a variety of cutaneous, systemic, and serologic features, which have resulted in a confusing array of names for this disorder(s).
UV likely represents a continuum of disease, ranging from urticaria with minimal vasculitis, to life- or organ-threatening systemic vasculitis with minimal urticaria. Some patients have low complement levels, a feature that is associated with more severe disease and with systemic involvement. By comparison, patients with normal complement levels are more likely to have mild disease (sometimes referred to as normocomplementemic urticarial vasculitis [NUV]).
See survey below! But to see the full list of all chronic urticaria go back to the main page. http://urticariaresearch.blogspot.com/ to post or comment in areas like: your health history,Things we should know about your urticaria, diet and other information.
What type of Urticaria have you been diagnosed with?
How Often ?
How are you feeling about your condition?
Have you been sucessful in finding treatment for your Urticaria?
What type of doctor have you seen?
What lab tests have you had?
Previous history of being diagnosed with Nephritis (kidney ) infection?
Have you been hospitalized for an infection in the past?
Muscle/Joint/Jaw/Neck Pain?
Dental problems/abcess/root canals?
NEW QUESTION Contact lens developing crystals?
Digestive issues?
Any issues after receiving childhood immunizations?
Food sensitivity/?
Had a significant vision change through the years?
MRI Brain/Angioma?
Don't forget to post "your" information!!
This site is dedicated to my husband who has battled chronic urticaria for over 29 years. For more information on your type of urticaria please click on this link http://urticariaresearch.blogspot.com/ to go back to the main page and review areas DOWN THE PAGE which include: WE NEED YOUR IMPUT TO LEARN MORE ABOUT THIS CONDITION! *Your Medical history before and after chronic urticaria *Things we should know about your urticaria *Need prayer *Does location play a part? *Do you have a question? *What are your symptoms and triggers? Together we can find a cure!
Urticaria and Lip Fasculation
ReplyDeleteUrticaria and Lip-fasciculation
Wilms Tumor and Urticaria
ReplyDeleteInteresting article on Wilms Tumor (Kidney) and Urticaria
Definition of Pseudotumor cerebri:
ReplyDeletePseudotumor cerebri: Increased pressure within the brain in the absence of a tumor. Symptoms may include headache, nausea, vomiting, pulsating intracranial noises, singing in the ears, double vision, loss of visual accuracy, and even blindness. It is most common in women between the ages of 20 and 50. The cause is usually not known. The condition is associated sometimes with the use of tetracycline, nalidixic acid, nitrofurantoin, phenytoin, lithium, and amiodarone, and the overuse of vitamin A. Diagnosis is by brain imaging and lumbar puncture. Drugs to reduce cerebrospinal fluid production or hyperosmotic drugs may be used to reduce fluid buildup. Excess cerebrospinal fluid may be removed by repeated spinal taps, shunting or a type of surgery called optic nerve sheath fenestration that allows the excess fluid to escape. Steroids may be prescribed to reduce swelling of brain tissue. Pseudotumor cerebri is also called benign intracranial hypertension.
Vasculitis with urticaria, hypocomplementemia, and multiple system involvement
ReplyDeleteP. U. Feig, N. A. Soter, H. M. Yager, L. Caplan and S. Rosen
A patient with cutaneous necrotizing vasculitis had chronic urticaria associated with multiple system involvement including arthralgias, glomerulonephritis, myositis, pseudotumor cerebri, and adenopathy. Persistent hypocomplementemia is noted with classic pathway activation. The syndrome recognized in this patient and those few individuals reported previously seems to constitute a distinct category of collagen-vascular disease.
Jama Journal Vasculitis with urticaria, hypocomplementemia, and multiple system involvement
P. U. Feig, N. A. Soter, H. M. Yager, L. Caplan and S. Rosen
Urticaria, nephritis, and pseudotumor cerebri.
ReplyDeleteDepartment of Rheumatic and Immunologic Disease, Cleveland Clinic Foundation, Ohio 44195.
The spectrum of chronic urticarial disease ranges from chronic urticarial skin lesions alone to well-characterized systemic lupus erythematosus with urticarial vasculitis as the major skin manifestation. Within this spectrum is the syndrome of urticarial vasculitis associated with systemic disease manifestations. There have been six previously recorded cases of urticarial vasculitis associated with pseudotumor cerebri. At least two of these have included membranoproliferative glomerulonephritis. The authors report a case of chronic urticarial disease associated with pseudotumor cerebri and membranoproliferative glomerulonephritis, but without demonstrable vasculitis. It is possible that this represents a distinct entity within the spectrum of chronic urticarial disease and cca be easily screened for in clinical practice.
PubMed Article on Urticaria, nephritis,and pseudotumor cerebri.
Definition of Vasculitis:
ReplyDeleteA varied group of disorders which all share a common underlying problem of inflammation of a blood vessel or blood vessels. The inflammation may affect any size blood vessel, anywhere in the body. It may affect either arteries and/or veins. The inflammation may be focal, meaning that it affects a single location within a vessel; or it may be widespread, with areas of inflammation scattered throughout a particular organ or tissue, or even affecting more than one organ system in the body.
Description
Urticarial vasculitis
ReplyDeleteAuthors
Jerry D Brewer, MD
Mark DP Davis, MD
Section Editors
John H Stone, MD, MPH
Sarbjit Saini, MD
Deputy Editor
Anna M Feldweg, MD
Last literature review version 16.3: October 2008 | This topic last updated: September 19, 2007 (More)
INTRODUCTION — Urticarial vasculitis (UV) is considered a clinicopathologic entity consisting of two elements:
Clinical manifestations of urticaria
Histopathological evidence of cutaneous leukocytoclastic vasculitis (LCV) of the small vessels, largely involving the postcapillary venules [1-4].
Although UV is most commonly idiopathic, it can occur in association with autoimmune diseases, drug reactions, infections, or malignancy. UV may be systemic or localized to the skin [5]. Hypocomplementemia, when present, may be associated with extensive vasculitis and systemic features that most commonly involve the musculoskeletal, pulmonary, renal, and/or gastrointestinal systems. Discussion of this topic is confounded by the lack of accepted criteria for distinguishing UV from other cutaneous vasculitides and associated conditions.
A detailed review of the literature has been published by the authors [6]. A practical approach is presented here. The epidemiology, clinical features, laboratory and biopsy findings, differential diagnosis, and prognosis of UV will be reviewed herein. (See "Etiology and diagnosis of urticaria" for a more general discussion of urticaria and related conditions).
TERMINOLOGY — UV is characterized by a variety of cutaneous, systemic, and serologic features, which have resulted in a confusing array of names for this disorder(s).
UV likely represents a continuum of disease, ranging from urticaria with minimal vasculitis, to life- or organ-threatening systemic vasculitis with minimal urticaria. Some patients have low complement levels, a feature that is associated with more severe disease and with systemic involvement. By comparison, patients with normal complement levels are more likely to have mild disease (sometimes referred to as normocomplementemic urticarial vasculitis [NUV]).
Urticarial Vasculitis
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ReplyDelete